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Current status

NosoGraph v0.2.1 · Public Alpha · 2026-08-22

NosoGraph is open-source research software for connecting biomedical knowledge, evidence, and provenance. It is for research use only, not medical advice, diagnosis, or clinical decision support. Live documentation is whatever SHA GitHub Pages currently serves from master; GitHub Pages is documentation, not the FastAPI app. The dashboard is local or self-hosted. There is no hosted public demo. Community/patient posting is not implemented.

Repository snapshot

Metric Value Kind
Discoverable modules 10,404 full-corpus (Disease.list_all())
On-disk module directories 10,406 full-corpus (includes 2 blocked slugs)
Harvest catalog entries 10,391 full-corpus (disease_registry.json)
Strict L2-validated modules 88 n=500 sample
L3 expression-curated (sample) 2 n=500 sample (ad, acute_myeloid_leukemia)
L3 consensus membership 23 full-corpus (CURATED_CONSENSUS_DISEASES)
Reference modules 6 full-corpus
CI-validated modules 8 full-corpus; hosted CI --strict
Registered pipeline adapters 25 full-corpus (list_modules())
Offline tests selected in v0.2.1 suite 2,445 snapshot (suite has grown; not a live collect-gate)

Authoritative file: public-status.yaml. Regeneration: python scripts/refresh_public_status.py. Harvest drift: python scripts/check_registry_harvest.py. Definitions: coverage.

Registry breadth is not curation depth. L2=88 is not “88 of 88 of the whole registry.” The retired “40+ pipelines” slogan mixed unregistered packages with adapters.

Capability maturity

Surface State Use it for
nosograph CLI STABLE Task-oriented local exploration and validation.
FastAPI API + dashboard BETA Local / self-hosted research interfaces. Not on GitHub Pages.
Evidence Explorer PUBLIC_ALPHA Read-only claim → evidence → provenance → source inspection (needs imported store).
Evidence Workspace BETA Multi-source evidence, claims, and ranked research hypotheses.
NosoGraph Compare BETA Deterministic 2–5-condition comparison with explicit missingness and exports.
Literature mining implemented Adapter + PubMed/Europe PMC connectors; not a separate “intelligence product.”
Open Targets synchronization EXPERIMENTAL A limited vertical sync slice and dry-run workflow.
DEMO_MODE implemented, default off Local opt-in write/job block. Not deployed.
Public hosted demo PLANNED Not deployed. No public app URL.
Optional LLM enrichment EXPERIMENTAL Not required for deterministic core workflows.
FHIR / OMOP / Phenopackets NOT_IMPLEMENTED No current interoperability implementation.
PyPI package NOT_IMPLEMENTED Install from source.

Maturity describes NosoGraph implementation state. Source maturity is tracked separately in the source matrix.

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